SuppRankedTop 10 lactase brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Lactase Best Sellers top 100. Updated October 15, 2026.
Physician's CHOICE is the top-selling lactase brand on Amazon by estimated revenue, at about $2.4M/mo from 4 products in the Lactase Best Sellers top 100. That is about 43% more than #2 LactoJoy (~$1.7M/mo). The list is fairly concentrated: the top 3 brands take about 38% of its estimated sales and the top 10 about 70%, spread across 45 brands in total. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Physician's CHOICE18% share · best #1 | $2.4M |
| 2 | LactoJoy13% share · best #4 | $1.7M |
| 3 | Intoleran7% share · best #33 | $896K |
| 4 | DairyPill7% share · best #5 | $895K |
| 5 | Milkaid7% share · best #18 | $881K |
| 6 | Nutrition Essentials6% share · best #2 | $749K |
| 7 | Milky4% share · best #7 | $573K |
| 8 | Vitamatic4% share · best #3 | $487K |
| 9 | Enzymedica3% share · best #11 | $457K |
| 10 | Puregen2% share · best #12 | $328K |
The top 10, brand by brand
1. Physician's CHOICE
~$2.4M/mo est. revenue (18% of this list) and ~57K units/mo from 4 products; best position #1. Its highest-ranked product here is Physician's CHOICE Bloat & Gas Probiotic 5-in-1 Proactive Support + Daily… at #1. Overall it ranks #37 of 3,479 brands.
2. LactoJoy
~$1.7M/mo est. revenue (13% of this list) and ~34.5K units/mo from 4 products; best position #4. Its highest-ranked product here is LactoJoy Lactase Pills 14,500 I 45 Pieces I Powerful Lactase Enzymes for… at #4. Overall it ranks #391 of 3,479 brands.
3. Intoleran
~$896K/mo est. revenue (7% of this list) and ~23.2K units/mo from 8 products; best position #33. Its highest-ranked product here is Intoleran Lactase 20,000 Digestive Enzymes - 50 Scored Tablets | Supplement for… at #33. Overall it ranks #296 of 3,479 brands.
4. DairyPill
~$895K/mo est. revenue (7% of this list) and ~29K units/mo from 4 products; best position #5. Its highest-ranked product here is DairyPill Lactase Enzyme Pills for Lactose Intolerance, 18000 FCC, 30 Ct at #5. Overall it ranks #455 of 3,479 brands.
5. Milkaid
~$881K/mo est. revenue (7% of this list) and ~45.6K units/mo from 12 products; best position #18. Its highest-ranked product here is Milkaid Lactase Enzyme Drops for Lactose Intolerance | Prevents Gas, Bloating &… at #18. Overall it ranks #315 of 3,479 brands.
6. Nutrition Essentials
~$749K/mo est. revenue (6% of this list) and ~30K units/mo from 1 product; best position #2. Its highest-ranked product here is Nutrition Essentials Probiotics for Women and Men - with Lactase Enzyme and… at #2. Overall it ranks #500 of 3,479 brands.
7. Milky
~$573K/mo est. revenue (4% of this list) and ~17.9K units/mo from 2 products; best position #7. Its highest-ranked product here is Milky Lactose Intolerance Pills - 10,800 FCC - Dairy Relief for Lactose… at #7. Overall it ranks #682 of 3,479 brands.
8. Vitamatic
~$487K/mo est. revenue (4% of this list) and ~25.1K units/mo from 2 products; best position #3. Its highest-ranked product here is Vitamatic Lactase Enzyme 9000 FCC 240 Tablets - Lactose Intolerance Relief… at #3. Overall it ranks #20 of 3,479 brands.
9. Enzymedica
~$457K/mo est. revenue (3% of this list) and ~15.8K units/mo from 2 products; best position #11. Its highest-ranked product here is Enzymedica Lacto Digestive Enzymes for Men & Women - 90 Capsules | Lactose… at #11. Overall it ranks #78 of 3,479 brands.
10. Puregen
~$328K/mo est. revenue (2% of this list) and ~16.6K units/mo from 2 products; best position #12. Its highest-ranked product here is Puregen Labs Dairy Relief Natural Lactase Enzyme 3000 FCC, 90 Caplets | Fast… at #12. Overall it ranks #288 of 3,479 brands.
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Full Lactase ranking
All 45 brands in the list, ordered by rank strength, plus the top 10 products.
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