SuppRankedTop 10 5-htp brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's 5-HTP Best Sellers top 100. Updated October 15, 2026.
NOW Foods is the top-selling 5-htp brand on Amazon by estimated revenue, at about $1.2M/mo from 5 products in the 5-HTP Best Sellers top 100. That is about 34% more than #2 Natrol (~$898K/mo). The list is fragmented: the top 3 brands take about 26% of its estimated sales and the top 10 about 60%, spread across 59 brands in total. About 10% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | NOW Foods11% share · best #1 | $1.2M |
| 2 | Natrol8% share · best #11 | $898K |
| 3 | Natural Factors7% share · best #3 | $785K |
| 4 | Designs for Health7% share · best #25 | $725K |
| 5 | Pure Encapsulations6% share · best #24 | $709K |
| 6 | Nutricost6% share · best #4 | $628K |
| 7 | Life Extension6% share · best #2 | $626K |
| 8 | THORNE4% share · best #9 | $408K |
| 9 | Doctor's Best3% share · best #6 | $351K |
| 10 | Dr. Emil3% share · best #8 | $333K |
The top 10, brand by brand
1. NOW Foods
~$1.2M/mo est. revenue (11% of this list) and ~67.5K units/mo from 5 products; best position #1. Its highest-ranked product here is NOW Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, 120 Veg Caps at #1. Overall it ranks #1 of 3,479 brands.
2. Natrol
~$898K/mo est. revenue (8% of this list) and ~32.3K units/mo from 5 products; best position #11. Its highest-ranked product here is Natrol 5-HTP 200 mg Time Release, Helps Support a Balanced Mood, 60 Tablets… at #11. Overall it ranks #54 of 3,479 brands.
3. Natural Factors
~$785K/mo est. revenue (7% of this list) and ~31.1K units/mo from 2 products; best position #3. Its highest-ranked product here is Natural Factors Suntheanine L-Theanine 100 mg, 60 Chewable Tablets | L-theanine… at #3. Overall it ranks #44 of 3,479 brands.
4. Designs for Health
~$725K/mo est. revenue (7% of this list) and ~13.6K units/mo from 4 products; best position #25. Its highest-ranked product here is Designs for Health NeuroCalm, Supports Mood & Stress Relief, 60 Capsules… at #25. Overall it ranks #26 of 3,479 brands.
5. Pure Encapsulations
~$709K/mo est. revenue (6% of this list) and ~12.1K units/mo from 3 products; best position #24. Its highest-ranked product here is Pure Encapsulations MotilPro, 180 Capsules | Hypoallergenic Dietary Supplement… at #24. Overall it ranks #3 of 3,479 brands.
6. Nutricost
~$628K/mo est. revenue (6% of this list) and ~34.2K units/mo from 2 products; best position #4. Its highest-ranked product here is Nutricost 5-HTP 200mg, 120 Vegetarian Capsules (5-Hydroxytryptophan) | GMO-Free… at #4. Overall it ranks #2 of 3,479 brands.
7. Life Extension
~$626K/mo est. revenue (6% of this list) and ~33.5K units/mo from 2 products; best position #2. Its highest-ranked product here is Life Extension L-Theanine, 200 mg, Relaxation, 60 Capsules | Amino Acid… at #2. Overall it ranks #11 of 3,479 brands.
8. THORNE
~$408K/mo est. revenue (4% of this list) and ~10.5K units/mo from 1 product; best position #9. Its highest-ranked product here is THORNE 5-HTP, 100 mg 5-Hydroxytryptophan & Active Vitamin B6, 90 Capsules… at #9. Overall it ranks #8 of 3,479 brands.
9. Doctor's Best
~$351K/mo est. revenue (3% of this list) and ~15.9K units/mo from 2 products; best position #6. Its highest-ranked product here is Doctor's Best L-Theanine Caps 150 mg, for Men & Women, 90 Veg Capsules at #6. Overall it ranks #24 of 3,479 brands.
10. Dr. Emil
~$333K/mo est. revenue (3% of this list) and ~13.7K units/mo from 2 products; best position #8. Its highest-ranked product here is Dr. Emil 200MG 5-HTP Plus, Mood & Sleep, L-Tryptophan, B6, SAM-e, 60 Count… at #8. Overall it ranks #553 of 3,479 brands.
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Full 5-HTP ranking
All 59 brands in the list, ordered by rank strength, plus the top 10 products.
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