Top 10 prebiotics brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Prebiotics Best Sellers top 100. Updated October 15, 2026.
Physician's CHOICE is the top-selling prebiotics brand on Amazon by estimated revenue, at about $1.6M/mo from 3 products in the Prebiotics Best Sellers top 100. That is about 52% more than #2 Metamucil (~$1M/mo). The list is fragmented: the top 3 brands take about 23% of its estimated sales and the top 10 about 50%, spread across 65 brands in total. About 17% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Physician's CHOICE10% share · best #1 | $1.6M |
| 2 | Metamucil7% share · best #2 | $1M |
| 3 | ProMix6% share · best #6 | $911K |
| 4 | Align6% share · best #14 | $869K |
| 5 | Lemme4% share · best #5 | $685K |
| 6 | Wholesome Wellness4% share · best #9 | $588K |
| 7 | Ritual4% share · best #12 | $570K |
| 8 | Benefiber3% share · best #4 | $539K |
| 9 | Gundry3% share · best #17 | $514K |
| 10 | Jarrow Formulas3% share · best #21 | $482K |
The top 10, brand by brand
1. Physician's CHOICE
~$1.6M/mo est. revenue (10% of this list) and ~61.6K units/mo from 3 products; best position #1. Its highest-ranked product here is Physician's CHOICE Probiotics for Women - PH Balance, Digestive, UT, & Feminine… at #1. Overall it ranks #37 of 3,479 brands.
2. Metamucil
~$1M/mo est. revenue (7% of this list) and ~43.7K units/mo from 1 product; best position #2. Its highest-ranked product here is Metamucil Fiber Gummies for Adults, No Sugar Added Orange Flavor, 5g Prebiotic… at #2. Overall it ranks #45 of 3,479 brands.
3. ProMix
~$911K/mo est. revenue (6% of this list) and ~15.4K units/mo from 1 product; best position #6. Its highest-ranked product here is Promix Nutrition Debloat Powder for Gut Health, Reduces Bloating, 30ct… at #6. Overall it ranks #220 of 3,479 brands.
4. Align
~$869K/mo est. revenue (6% of this list) and ~28.8K units/mo from 4 products; best position #14. Its highest-ranked product here is Align Dualbiotic, Prebiotics and Probiotics for Women and Men, Probiotics for… at #14. Overall it ranks #135 of 3,479 brands.
5. Lemme
~$685K/mo est. revenue (4% of this list) and ~22.9K units/mo from 2 products; best position #5. Its highest-ranked product here is Lemme Debloat Digestive & Gut Health Gummies, 30-Day Supply | 2 Clinically… at #5. Overall it ranks #46 of 3,479 brands.
6. Wholesome Wellness
~$588K/mo est. revenue (4% of this list) and ~21.7K units/mo from 2 products; best position #9. Its highest-ranked product here is Wholesome Wellness Dr. Formulated Raw Probiotics for Women 100 Billion CFUs… at #9. Overall it ranks #187 of 3,479 brands.
7. Ritual
~$570K/mo est. revenue (4% of this list) and ~9.5K units/mo from 1 product; best position #12. Its highest-ranked product here is Ritual Synbiotic+ 3-in-1 Probiotic Supplement - 30 Capsules - 30 Servings… at #12. Overall it ranks #67 of 3,479 brands.
8. Benefiber
~$539K/mo est. revenue (3% of this list) and ~33.1K units/mo from 2 products; best position #4. Its highest-ranked product here is Benefiber Prebiotic Fiber Supplement Gummies, Assorted Fruit Flavor, 81 Ct… at #4. Overall it ranks #113 of 3,479 brands.
9. Gundry
~$514K/mo est. revenue (3% of this list) and ~7.4K units/mo from 1 product; best position #17. Its highest-ranked product here is Gundry MD Bio Complete 3, 3-in-1 Probiotics, Pre & Postbiotics, 30 Servings… at #17. Overall it ranks #1064 of 3,479 brands.
10. Jarrow Formulas
~$482K/mo est. revenue (3% of this list) and ~11K units/mo from 2 products; best position #21. Its highest-ranked product here is Jarrow Formulas Lactoferrin Supplements 250 mg - Immune-Supporting Glycoprotein… at #21. Overall it ranks #32 of 3,479 brands.
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Full Prebiotics ranking
All 65 brands in the list, ordered by rank strength, plus the top 10 products.
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