SuppRankedTop 10 probiotics brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Probiotics Best Sellers top 100. Updated October 15, 2026.
Garden of Life is the top-selling probiotics brand on Amazon by estimated revenue, at about $6.4M/mo from 9 products in the Probiotics Best Sellers top 100. That is about 57% more than #2 Physician's CHOICE (~$4.1M/mo). The list is fairly concentrated: the top 3 brands take about 38% of its estimated sales and the top 10 about 70%, spread across 49 brands in total. About 11% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Garden of Life17% share · best #2 | $6.4M |
| 2 | Physician's CHOICE11% share · best #1 | $4.1M |
| 3 | Align10% share · best #14 | $3.8M |
| 4 | Seed9% share · best #4 | $3.3M |
| 5 | Culturelle8% share · best #5 | $3M |
| 6 | Lemme5% share · best #10 | $1.8M |
| 7 | Florastor4% share · best #7 | $1.5M |
| 8 | Microbiome Labs2% share · best #27 | $817K |
| 9 | AZO2% share · best #30 | $782K |
| 10 | BIOMA2% share · best #16 | $780K |
The top 10, brand by brand
1. Garden of Life
~$6.4M/mo est. revenue (17% of this list) and ~231K units/mo from 9 products; best position #2. Its highest-ranked product here is Garden of Life Dr. Formulated Once Daily Women's Probiotics, 50B CFU, 30ct | 50… at #2. Overall it ranks #15 of 3,479 brands.
2. Physician's CHOICE
~$4.1M/mo est. revenue (11% of this list) and ~208K units/mo from 3 products; best position #1. Its highest-ranked product here is Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics… at #1. Overall it ranks #26 of 3,479 brands.
3. Align
~$3.8M/mo est. revenue (10% of this list) and ~97.5K units/mo from 9 products; best position #14. Its highest-ranked product here is Align Probiotic, Pro Formula, Probiotics for Women and Men, Probiotics for… at #14. Overall it ranks #72 of 3,479 brands.
4. Seed
~$3.3M/mo est. revenue (9% of this list) and ~55K units/mo from 1 product; best position #4. Its highest-ranked product here is Seed DS-01 Daily Synbiotic - Adult Probiotic + Prebiotic - 30-Days with Jar… at #4. Overall it ranks #152 of 3,479 brands.
5. Culturelle
~$3M/mo est. revenue (8% of this list) and ~118K units/mo from 6 products; best position #5. Its highest-ranked product here is Culturelle Pro Strength Probiotics for Digestive Gut Health*, 12B CFU, 60ct… at #5. Overall it ranks #59 of 3,479 brands.
6. Lemme
~$1.8M/mo est. revenue (5% of this list) and ~60K units/mo from 2 products; best position #10. Its highest-ranked product here is Lemme Purr Vaginal Probiotic Gummies for Women, 30-Day Supply | Balanced pH… at #10. Overall it ranks #38 of 3,479 brands.
7. Florastor
~$1.5M/mo est. revenue (4% of this list) and ~28.5K units/mo from 2 products; best position #7. Its highest-ranked product here is Florastor Probiotic for Digestive and Immune Health, 100 Capsules | Probiotics… at #7. Overall it ranks #195 of 3,479 brands.
8. Microbiome Labs
~$817K/mo est. revenue (2% of this list) and ~12.3K units/mo from 1 product; best position #27. Its highest-ranked product here is Microbiome Labs Mega SporeBiotic Daily Probiotic for Women + Men, 60 Ct at #27. Overall it ranks #428 of 3,479 brands.
9. AZO
~$782K/mo est. revenue (2% of this list) and ~30K units/mo from 2 products; best position #30. Its highest-ranked product here is AZO Complete Feminine Balance Daily Vaginal Probiotics for Women, 30 Count… at #30. Overall it ranks #61 of 3,479 brands.
10. BIOMA
~$780K/mo est. revenue (2% of this list) and ~15K units/mo from 1 product; best position #16. Its highest-ranked product here is BIOMA Probiotics - Digestive Health Probiotic - Gut Support for Men & Women… at #16. Overall it ranks #296 of 3,479 brands.
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Full Probiotics ranking
All 49 brands in the list, ordered by rank strength, plus the top 10 products.
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